Does Retinal Ganglion Cell Loss Precede Visual Field Loss in Glaucoma?
نویسندگان
چکیده
منابع مشابه
Estimating the rate of retinal ganglion cell loss in glaucoma.
PURPOSE To present and evaluate a new method of estimating rates of retinal ganglion cell (RGC) loss in glaucoma by combining structural and functional measurements. DESIGN Observational cohort study. METHODS The study included 213 eyes of 213 glaucoma patients followed up for an average of 4.5 ± 0.8 years with standard automated perimetry visual fields and optical coherence tomography. A c...
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PURPOSE We determined the time lag between loss of retinal ganglion cell function and retinal nerve fiber layer (RNFL) thickness. METHODS Glaucoma suspects were followed for at least four years. Patients underwent pattern electroretinography (PERG), optical coherence tomography (OCT) of the RNFL, and standard automated perimetry testing at 6-month intervals. Comparisons were made between chan...
متن کاملHow does glaucoma look?: patient perception of visual field loss.
OBJECTIVE To explore patient perception of vision loss in glaucoma and, specifically, to test the hypothesis that patients do not recognize their impairment as a black tunnel effect or as black patches in their field of view. DESIGN Clinic-based cross-sectional study. PARTICIPANTS Fifty patients (age range, 52-82 years) with visual acuity better than 20/30 and with a range of glaucomatous v...
متن کاملSelective loss of retinal ganglion cells in albino avian glaucoma.
Retinal ganglion cell loss was investigated in the retinae of albino quails before and after the development of glaucoma. The isodensity maps of ganglion cells, the total number of ganglion cells, and the histograms of the cell size in the central region of the retina were similar between albino quails without glaucoma and pigmented quails. However, ganglion cells in the intermediate and periph...
متن کاملTopography of neuron loss in the retinal ganglion cell layer in human glaucoma.
AIM To determine if retinal ganglion cell (RGC) loss influences the loss of surrounding RGCs to generate clustered patterns of cell death in human glaucoma. It is hypothesised that retinal ganglion cell loss accelerates the loss of surrounding cells to generate, at a local, cellular scale, clustered patterns of retinal of RGC death. The absence of these interactions would result in a diffuse pa...
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ژورنال
عنوان ژورنال: Journal of Glaucoma
سال: 2019
ISSN: 1057-0829
DOI: 10.1097/ijg.0000000000001380